Getting started with Visual PDC
Visual PDC provides research-grade tools for peptide–drug conjugate (PDC) design: molecular weight (DPR), stability from peptide sequence, and 3D structure viewing (PDC 3D Structure, Payload Attachment Site, Peptide-Drug Complex). All in the browser; no installation required.
What we offer
Enter peptide sequence and drug (SMILES) with optional linker to get total mass, charge, pI, and logP from PDC Molecular Weight (DPR). Use Stability Calculator for stability indices from peptide sequence. View peptide–drug 3D in PDC 3D Structure, Payload Attachment Site, or Peptide-Drug Complex; export PDB, PNG, and PDC Report Export (PDF, CSV). Export options: Export formats, PDC Report Export.
Typical workflow
- PDC mass: Go to PDC Molecular Weight (DPR), enter peptide (sequence or UniProt ID), drug (SMILES or PubChem), and optional linker. Get peptide/drug/linker mass, total mass, charge, pI, logP, and a PDF report.
- Stability: Use Stability Calculator for stability indices and physicochemical properties from the peptide moiety.
- 3D view: Use PDC 3D Structure to load a peptide–drug or PDC PDB; use Peptide-Drug Complex to upload your own file. Export PDB or PNG from the viewer.
- Payload attachment: Use Payload Attachment Site for multi-frame or payload-attachment preview; export PNG.
- Export: See PDC Report Export and Export formats for where to export reports and structures.
Tools at a glance
- PDC Molecular Weight (DPR) — Peptide + drug (SMILES) + optional linker → total mass, charge, pI, logP; PDF report.
- Stability Calculator — Stability indices and physicochemical properties from peptide sequence.
- PDC 3D Structure — Load peptide–drug or PDC PDB; view, export PDB/PNG.
- Payload Attachment Site — Multi-frame or payload-attachment preview; export PNG.
- Peptide-Drug Complex — Upload PDC or peptide–drug PDB; view and export.
Export: Export, Export formats, PDC Report Export.
Docs and reference
- PDC Design — Peptide carrier, linker, payload, stability, release.
- Data sources — DrugBank, PDB, PubChem, UniProt.
- Tutorials — Step-by-step for PDC Molecular Weight, Stability Calculator, 3D viewer, PDC Report Export.
- API — Programmatic access.